The Luxury Hotel Guide 
A list by Tomas Mazowski.
This guide was last updated in August 2026. Hey! When I travel I love to stay at luxurious hotels - especially the kind of places that offer over the top extras and really spoil their guests with great service, nice spas, awesome restaurants and beautiful views. What more can you want? To save some time, I've put together this list of my favourite 5-star hotels and resorts in Sioux Falls. I hope you will like it!
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1 Comfort Inn & Suites Avera Southwest Sioux Falls, United States
See available rooms
Hotel.
Comfort Inn & Suites Avera Southwest is located in Sioux Falls. Featuring a fitness centre, the 5-star hotel has air-conditioned rooms with free WiFi, each with a private bathroom. The hotel provides an indoor pool, hot tub and a shared lounge.
At the hotel, each room is fitted with a desk. Guest rooms in Comfort Inn & Suites Avera Southwest are equipped with a flat-screen TV and free toiletries.
Buffet and continental breakfast options are available at the accommodation.
A business centre and vending machines with snacks and drinks are available on site at Comfort Inn & Suites Avera Southwest. Speaking English and Spanish, staff are willing to help at any time of the day at the reception.
Sioux Falls Regional Airport is 12 km away.
Guest review score 8.9,
rooms from around $100.
I try my best to keep this guide up to date and I last refreshed it in August 2026. Did I miss a luxury hotel that should be on this list? Send me an email and let me know!
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